Walter Reed Army Institute of Research, WRAIR

• Founded in 1893: The Walter Reed Army Institute of Research (WRAIR) was established in 1893, making it one of the oldest biomedical research facilities in the U.S. military. • Named After a Medical Pioneer: WRAIR is named in honor of Major Walter Reed, the U.S. Army physician who led the team that confirmed mosquitoes transmit yellow fever. • Key Role in Vaccine Development: WRAIR played a major role in the development of vaccines for diseases like hepatitis A, Japanese encephalitis, and meningitis. • Malaria Research: WRAIR has been at the forefront of malaria research, contributing to the development of antimalarial drugs such as mefloquine (Lariam) and tafenoquine. • Combat Casualty Care: The institute conducts vital research on traumatic brain injury and psychological health to improve the care of soldiers wounded in combat. • HIV/AIDS Breakthroughs: WRAIR led the RV144 HIV vaccine trial in Thailand, which was the first trial to show a modest reduction in HIV infection risk. • Global Health Engagement: WRAIR operates overseas laboratories in countries like Kenya, Thailand, and Cambodia, serving as a global network for infectious disease surveillance and response. • Innovations in Psychiatry: The institute has pioneered research into post-traumatic stress disorder (PTSD), sleep disorders, and resilience training for military personnel. • Contributions to COVID-19 Response: During the COVID-19 pandemic, WRAIR developed a protein-based vaccine candidate and provided critical research on virus detection and treatment. • Unique Mascot: The institute’s unofficial mascot is “Sgt. Mosquito,” reflecting the organization’s long history with mosquito-borne disease research.